Feel free to download, print and bring along your own copy of the programme book: Barntumörbanken Symposium 2022 – Programme book

Thursday 1 December

11:00 – 12:30 REGISTRATION and LUNCH

12:30 – 12:50 The Swedish Childhood Tumour Biobank
Welcome address
Johanna Sandgren, Karolinska Institutet and Karolinska University Hospital; Gustaf Ljungman, Uppsala University Hospital and Uppsala University

12:50 – 14:30 Clinical genomics and targeted therapies in the pediatric cancer field
Chairs: Gustaf Ljungman, Per Kogner

12:50 – 13:30 INFORM and the Heidelberg experience (live streamed)
Olaf Witt, The German Cancer Research Center (DKFZ), Germany

13:30 – 14:10 Clinical sequencing at St Jude
Jinghui Zhang, St. Jude Children’s Research Hospital, USA

14:10 – 14:30 Genomic Medicine Sweden and pediatric cancer patients
David Gisselsson Nord, Lund University, Sweden

14:30 – 15:00 COFFEE and POSTER VIEWING

15:00 – 15:40 Novel targets and therapies in pediatric cancer medicine
Chairs: Klas Blomgren, Jakob Stenman

15:00 – 15:20 PDX- models for CNS tumours and The Preclinical Cancer Treatment (PCT) Center
Fredrik Swartling, Uppsala University, Sweden

15:20 – 15:40 New treatments and models of neuroblastomas
Daniel Bexell, Lund University, Sweden

15:40 – 16:00 Science for Life Laboratories Precision Medicine Initiatives
Chairs: Klas Blomgren, Jakob Stenman

15:40 – 16:00 Systems medicine based diagnostics development for precision medicine
Janne Lehtiö, Karolinska Institutet, Sweden

16:00 – 17:00 Novel molecular technology and diagnostics
Chairs: Teresita Diaz de Ståhl, Anna Hagström

16:00 – 16:20 Spatial transcriptomics in pediatric brain tumours
Linda Kvastad, The Royal Institute of Technology, Sweden

16:20 – 16:40 Cell free tumour DNA analysis in pediatric CNS tumours
Emma Tham, Karolinska Institutet, Sweden

16:40 – 17:00 Clonal architecture of human neuroblastoma
Ninib Baryawno, Karolinska Institutet, Sweden

18:30 Conference dinner, restaurant Haga Bottega
For more information, please visit https://www.btbsymposium2022.se/dinner/

Friday 2 December

08:30 – 09:00 REGISTRATION

09:00 – 10:00 Epigenomics
Chairs: Magnus Sabel, Ingrid Øra

09:00 – 09:40 Classifying sarcomas by methylation analyses
Andreas von Deimling, The German Cancer Research Center (DKFZ), Germany

09:40 – 10:00 Improved diagnostics of pediatric CNS tumours based on DNA methylation classification
Helena Carén, University of Gothenburg, Sweden

10:00 – 10:30 COFFEE and POSTER VIEWING

10:30 – 12:10 Large scale biobanking and sequencing
Chairs: Johanna Sandgren, Valtteri Wirta

10:30 – 10:50 National strategies for biobanks in healthcare and research
Anna Beskow, Biobank Sweden, Sweden

10:50 – 11:20 U-CAN- collections of biomaterials and clinical information from adult cancer patients in Sweden
Tobias Sjöblom, Uppsala University, Sweden

11:20 – 11:40 Genomic Medicine Sweden
Richard Rosenquist Brandell, Karolinska Institutet, Sweden

11:40 – 11:55 The Norwegian Childhood Cancer Biobank (NCCB) – experiences and challenges
Lars O. Baumbusch, Oslo University Hospital, Norway

11:55 – 12:10 Development and strategies for the National Genomics Infrastructure
Tuuli Lappalainen, The Royal Institute of Technology, Sweden

12:10 – 13:10 LUNCH and POSTER VIEWING

13:10 – 13:30
Remarks from Karolinska Institutet, Jonas Bergh, Director Cancer Research; Karolinska University Hospital, Annika Tibell, Director Research, Education, Development and Innovation and Barncancerfonden, Britt-Marie Frost, Head of Department, Research and Education

13:30 – 14:30 Pediatric cancer genomic and pathology
Chairs: Monica Nistér, Susan Pfeifer

13:30 – 14:10 Histone mutations in DIPG
Cynthia Hawkins, The Hospital for Sick Children, University of Toronto, Canada

14:10 – 14:30 Lessons from gene expression for combination chemotherapy and immunotherapy
Nikolas Herold, Karolinska Institutet and Karolinska University Hospital, Sweden

14:30 – 15:00 COFFEE and POSTER VIEWING

15:00 – 16:00 Pediatric cancer predisposition
Chairs: David Gisselsson Nord, Emma Tham

15:00 – 15:40 Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency
Eric Bouffet, The Hospital for Sick Children, University of Toronto, Canada

15:40 – 16:00 Childhood Cancer Predisposition (ChiCaP)
Ann Nordgren, Karolinska Institutet, Karolinska University Hospital, Sahlgrenska University hospital and University of Gothenburg, Sweden

16:00 – 16:20 Selected presentations from submitted abstracts 
Chairs: David Gisselsson Nord, Emma Tham

16:00 – 16:10 Lorlatinib monotherapy for ALK mutated neuroblastoma relapses – an uncharted course
Torben Ek, Children´s Cancer Centre, Sweden

16:10 – 16:20 The irradiation-induced deterioration of gamma oscillations in the juvenile mouse brain is prevented by lithium treatment
Carlos Rodrigues, Karolinska Institutet, Sweden

16:20 – 16:30 Concluding remarks and best poster award
Gustaf Ljungman and Johanna Sandgren